Baseball's two best teams will meet this weekend not in Los Angeles or New York or Philadelphia. The AL-best Detroit Tigers will host the NL-best Chicago Cubs for a three-game interleague series at Comerica Park.

Friday in the opener of a 3-game series. First pitch from Comerica Park is set for 7:10 p.m. ET (Apple TV). Let's analyze BetMGM Sportsbook's MLB odds around the Cubs vs. Tigers odds and make our expert MLB picks and predictions for the best bets.

Detroit split a series with the Chicago White Sox earlier this week losing the series finale yesterday 3-2 in ten innings. Wenceel Perez went 2-4 with a home run in the loss for the Tigers. The Cubs took two of three against the Nationals winning yesterday 7-1. Ian Happ went 3-6 and drove in four runs to lead the rout for Chicago.