Inborn errors of bile acid synthesis are rare genetic disorders that can present as neonatal cholestasis, neurologic disease or fat-soluble-vitamin deficiencies. There are nine known defects of bile ...
While TbELO1–3 elongate C4 primer to C18, TbELO4 functions as a polyunsaturated FA ELO that lengthens arachidonate (C20:4) salvaged from the host. In addition to TbELO1–4 orthologues, L. major has ...
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