Temperature is a key physiological factor that determines the speed of immune reactions. While this may seem obvious, it has remained largely unexplored at the single-cell level-until now.

This is a preview. Log in through your library . Abstract Although it is generally believed that phosphorylation of the regulatory light chain of myosin is required before smooth muscle can develop ...

This is a preview. Log in through your library . Abstract Myosin light chain phosphorylation in permeable skeletal muscle fibers increases isometric force and the rate of force production at ...

(September 29, 2005, La Jolla, CA) Scientists from the Burnham Institute for Medical Research and the University of Vermont have captured the first 3-dimensional (3D) atomic-resolution images of the ...

Cell generated force plays essential roles in a wide range of biological processes, such as cell motility, cytokinesis, and tissue morphogenesis. In a study published in Nature Communications, a ...

The novel cardiac myosin inhibitor aficamten improved peak oxygen uptake in symptomatic obstructive hypertrophic cardiomyopathy (HCM), the pivotal SEQUOIA-HCM trial showed. At 24 weeks, the mean ...

Over the last several years the identification and functional characterization of the motor proteins actin and myosin in the nucleus has initiated a change in the view of nuclear processes. It is now ...