A hidden atrial dysfunction may raise stroke risk in people with transthyretin amyloid cardiomyopathy (ATTR-CM); however, a noninvasive assessment tool may help identify those at increased risk, ...

Each cardiac muscle cell can have over 5,000 sarcomeres, which compounds both the shortening and relaxation events. "This process appears to be regulated by myosin-binding protein-C (cMyBP-C), which ...

An experimental Cytokinetics drug has Phase 3 data showing it improved the ability of the heart to work during exercise. In addition to meeting this main goal of its pivotal test in a rare ...

ROCKVILLE, MD – In a surprising discovery, scientists have found that the heart possesses "sweet taste" receptors, similar to those on our tongues, and that stimulating these receptors with sweet ...

Meaghan started at UMass Lowell in the fall of 2019 where she joined Professor Jeffrey Moore's lab. Her research is focused on the mechanism of sarcomere proteins in heart muscle contraction. She aims ...

Mammalian hearts have almost no ability to grow new heart muscle cells, called cardiomyocytes, after birth. Thus, dead tissue after an adult heart attack is not repaired with new cardiomyocytes. It is ...

The Fowler laboratory studies cellular architecture: how cells spatially organize themselves and their interior compartments to achieve intricate geometries, mechanical strength, and physiological ...

The human heart is a highly complex pump made of muscle, complete with its own electric power system, supplying the energy and oxygen it needs to function. The heart’s pumping action is regulated by ...

The heart is a muscle like no other, beating 60 to 100 times per minute on average, around the clock. But when it grows weak, it can lead to serious problems: from debilitating shortness of breath and ...