Mechanisms of heart-valve disease often mimic processes observed in embryonic and early childhood development, including activation of valvular interstitial cell (VIC) phenotypes and remodeling of ...

BACKGROUND: Aortic valve calcification increases leaflet stiffness and contributes to the development of calcific aortic valve disease. The molecular and cellular mechanisms underlying calcification ...

Researchers from the University of Basel in Switzerland have identified a key regulator gene for the formation of cardiac valves - a process crucial to normal embryonic heart development. These ...

Researchers have now proposed a molecular mechanism that links amyloid deposition in the aortic valve with degenerative calcification. They also theorize that other risk factors for CAVD, such as high ...

Researchers create biodegradable heart valves using shape-memory polymers and 3D bioprinting for safer cardiovascular procedures.

Fraunhofer IOF, startup NovaPump, and Jena University Hospital’s “pump cage” is cut out of a thin metal tube by laser. On the occasion of World Heart Day on September 29, the team reviewed the history ...

A startup that aims to integrate robotics with minimally invasive heart valve procedures has collected $31.4 million in venture capital funding. While robots have made inroads in many different types ...

A bicuspid aortic valve may present few problems throughout your life. But you’ll still need to live a heart-healthy lifestyle and monitor your cardiovascular system to prevent complications. The ...