Current therapies for rheumatoid arthritis rely on sustained immunosuppression rather than restoration of immune tolerance, with off-drug remission remaining rare.

Strong initial responses in 4 of 6 patients after many standard drugs had failed ...

New preclinical and translational findings position DNase I as a potentially transformative adjunct therapy for CAR-T ...

Legend Biotech (LGND) stock jumps as the company posts early-stage trial data for in vivo CAR-T cell therapy in B-cell ...

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a promising new way to improve CAR-T cell therapy for solid tumors such as lung cancer and melanoma. The study, published ...

Hanzlik's multiple sclerosis was destroying her freedom to live the life she wanted. She gave up her active nursing job for a ...

CAR T-cell therapy has been hugely successful in treating certain types of tumours, and stiffening up cancer cells beforehand could make it even more effective ...

We also report on a new use for artificial intelligence that could help eliminate some racial inequities in heart disease ...

Formation of an immunological synapse (gray) between CAR-T cells, which are specially equipped to express the CCR7 receptor(cyan), and tumor cells (magenta). The CAR ...