Mitochondria are essential for cell survival, repair, and adaptation. Not only do they generate most of the energy needed ...

Cells manage a wide range of functions in their tiny package — growing, moving, housekeeping, and so on — and most of those functions require energy. But how do cells get this energy in the first ...

Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...

Sickle cell disease is often thought of solely as a blood disorder, but new research from the Wood Neuro Research Group ...

Many biological functions are regulated by the switching on and off of mechanisms triggered by the matching of a keyhole ...

Scientists hoping to discover better ways to boost immune function — which could lengthen our healthspan and protect immunocompromised patients — may have a new target, according to findings published ...

In the rapidly evolving field of drug discovery, single-cell analysis has become an invaluable tool for understanding cellular heterogeneity and molecular pathways. However, traditional single-cell ...

These findings from research into diffuse large B cell lymphoma (DLBCL) are based on analyses of human patients and a murine model. The immunosuppressive role of fibroblastic reticular cells (FRCs) in ...

Short-term IF boosts glucose homeostasis, but prolonged fasting in adolescence may impair β cell maturation—potentially linking chronic IF to type 1 diabetes risk. Study: Chronic intermittent fasting ...

Teplizumab, a humanized monoclonal antibody to CD3 on T cells, is approved by the Food and Drug Administration to delay the onset of clinical type 1 diabetes (stage 3) in patients 8 years of age or ...

Mitochondrial transplantation is an emerging technique aimed at restoring cellular energy production in diseases marked by ...