Downstream bioprocessing steps have long been a challenge to drug manufacturers, particularly the chromatography step for purification of monoclonal antibodies (mAbs). The complexity of traditional ...

Simulated moving bed chromatography uses a counter-current to allow continuous chromatographic separations, which allows researchers to extract more analyte whilst using less packing material and ...

Although biopharmaceutical manufacturing covers an extensive range, it is essential that each iteration of a unit operation is in compliance with an unyielding set of operational parameters and ...

Matt Taylor is a senior process development associate at KBI Biopharma, where he focuses on the design, optimization, and scale-up of purification processes for biopharmaceutical manufacturing. Matt ...

Flash column chromatography is a method of chemical separation that is used to purify chemical mixtures. It is also known as flash purification, due to its function as a purification method. It is ...

Monolithic columns represent a significant advancement in liquid chromatography, utilising a continuous, porous structure to facilitate rapid and efficient separations. Unlike traditional packed ...

Fc receptor based affinity chromatography is a new emerging field of Fc functionality analytics. FcRn affinity columns separate antibody species that differ in their affinity to FcRn using conditions ...

Troubleshooting in gas chromatography has become much simpler over the years, with modern systems often having automated diagnostics that help ensure proper operation. However, not all troubleshooting ...

Flash column chromatography was developed in 1978 as an alternative method to long column chromatography. The method aims to isolate a component from a mixture and thereby purify it. It was built from ...