Development plans typically identify comparators that will meet regulatory needs and go some way to meeting the needs of other stakeholders in key markets. However, there is increasing recognition ...

Rigorous scientific standards are needed to address the challenge of providing information on the real-world effects of treatments and procedures. With enactment of healthcare reform legislation now a ...

Steven D. Pearson ( [email protected]) is president of the Institute for Clinical and Economic Review, in Boston, Massachusetts. Peter B. Bach is an associate attending physician at Memorial ...

The history of the new CER initiative in the United States, along with the evolving ways that evidence of comparative effectiveness is being applied to the coverage, payment, and pricing for oncology ...

Despite the scope and breadth of the new US health reform law, it contains little that observers see as likely to curtail the rising cost of care. This conclusion may be premature; the bill passed by ...

Using Health Technology Assessment to Identify Gaps in Evidence and Inform Study Design for Comparative Effectiveness Research Authors: Sean R. Tunis [email protected] and Charles Turkelson ...

Clinical validity—the association between genotype and clinical phenotype—is now available for an increasing number of genomic applications. On the other hand, clinical utility—the improvement in ...

Comparing the risks and benefits of new drugs against those already on the market will help ensure that patients receive the best treatment, but a lack of data is hindering GPs and clinicians, finds ...