No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...

New study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...

Mutations are changes in the molecular 'letters' that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including ...

The mutation in the huntingtin (HTT) gene, which causes the incurable, dominantly inherited Huntington’s disease, was identified decades ago, following one of the most closely watched disease gene ...

Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key tumor-suppressing pathways, opening up new avenues for blood cancer ...

Scientists at Duke-NUS Medical School and the National University Health System (NUHS), together with an international team ...

A genetic mutation commonly found in cancer patients may also affect how the human body develops in the womb, according to new research from the University of Dundee. Subscribe to our newsletter for ...

Characteristics of Clonal Hematopoiesis (CH) Mutations - a) We identified somatic mutations in known clonal hematopoiesis of indeterminate potential (CHIP) driver genes using peripheral blood ...

A new study has revealed that a single genetic mutation, found in all modern humans but absent in Neanderthals and Denisovans ...

Researchers at Weill Cornell Medicine report that a rare gene mutation that delays Alzheimer’s disease does so by damping inflammatory signaling in brain-resident immune cells in a preclinical study.

Duke-NUS and NUHS scientists uncover a complex web of genetic, age-related and microbial factors that increase the risk of stomach cancer.Age-related blood cell mutations may trigger early changes in ...