New molecular insights into the link between hepatocellular carcinoma and intratumoral fibrosis could lead to better ...

A research team has conducted a study exploring the role of the mannose pathway in regulating cell fate decisions in low glucose environments. Their work may hold potential for novel therapeutic ...

The Wei lab is interested in the regulation of cell signaling and tissue homeostasis by metalloproteinases and other proteins in development and disease. Project 1. The mechanisms of neural crest ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Amyotrophic lateral sclerosis (ALS) is a serious and usually fatal neurodegenerative disorder in which motor neurons deteriorate and die. The disease causes a loss of movement that eventually affects ...

A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...

Between 2% and 3% of all live-born infants are estimated to have a major developmental defect identified at birth (ICBD 1991; CDC 1995; Holmes 1997; March of Dimes 1999). The percentage increases ...

A research team has conducted a study exploring the role of the mannose pathway in regulating cell fate decisions in low glucose environments. Their work may hold potential for novel therapeutic ...

Australian researchers have uncovered a crucial new mechanism that helps explain how the heart’s major blood vessels form during early development, and how disruptions to this process can lead to ...

Researchers have uncovered a surprising molecular chain reaction in the brain that may play a role in some forms of autism.