Our connectivity results suggest that stimulation of the ventral tegmental area's dopaminergic pathways has the potential to ...

Learn more about eLife assessments Sleep disturbances are associated with poor long-term memory (LTM) formation, yet the underlying cell types and neural circuits involved have not been fully decoded.

Northwestern Medicine investigators have uncovered new insights into how metabolic dysfunction contributes to Parkinson's ...

research suggests that certain dopaminergic pathways may also be important in relieving depression-like symptoms. Research in humans has demonstrated that for some individuals with treatment-resistant ...

in particular those associated with the nigrostriatal dopaminergic pathway. There is now robust experimental evidence for a neuroprotective effect of nicotine upon dopaminergic neurons.

A subset of Parkinson’s disease is caused by CHCHD2, a gene which encodes a protein contained in the mitochondria of cells.

5 Sure enough, researchers found that dopaminergic neurons in the ventral tegmental area (VTA) were more active during sleep deprivation, and that suppressing their activity abolished most of the ...

Precision drugs and gene therapy treatments to activate pro-survival pathways in selected neuronal populations We investigate molecular mechanisms promoting functional maintenance of dopaminergic ...