During embryonic development, the entire nervous system, the skin and the sensory organs emerge from a single sheet of cells known as the ectoderm. While there have been extensive studies of how this ...

Embryonic patterning involves the complex interplay of multiple signalling pathways triggering gene regulatory networks, which, in turn, drive cell-fate choices and progenitor cell differentiation.

Bioscientists develop a method to observe patterns of early embryonic development, during which ectodermal cells diverge toward their fates as skin, organs and the nervous system. During embryonic ...

Collaborative work has developed a cell culture system that differentiates human pluripotent stem cells to amniotic ectoderm and surface ectoderm based on cell density. Research conducted by Dr Shota ...

Bone morphogenetic protein (BMP) inhibits neural specification and induces epidermal differentiation during ectodermal patterning. However, the mechanism of this process is not well understood. Here ...