How do single cells communicate in a tissue? How can these interactions be modeled, while retaining information of spatial context? Researchers around Fabian Theis from Helmholtz Munich Computational ...

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...

Gene regulatory networks (GRNs) depict the regulatory mechanisms of genes within cellular systems as a network, offering vital insights for understanding cell processes and molecular interactions that ...