Findings on Fugu gene splicing could help scientists develop pufferfish transgenes for mammalian cells, say researchers at Massachusetts Institute of Technology. The Fugu genome contains all the ...

Researchers at the Center for Genomic Regulation (CRG) in Barcelona have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine inside every cell. The ...

Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology. The vast majority of human genes -- more than nine in ten -- ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

On some level, biology is all about regulation, regulation, regulation. One way that our cells regulate their genes is through a process called alternative splicing, which entails the selective ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes with entire human sequences has posed significant technical challenges.

A human-specific NOVA1 variant changed mouse vocalizations, potentially providing insights into the evolution of language. Darnell said the switch to the new NOVA1 variant likely occurred between ...