No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...

Nature and nurture both determine how likely you are to develop a particular disease. Hiroshi Watanabe/DigitalVision via Getty Images Sitting in my doctor’s examination room, I was surprised when she ...

When two defective gene variants combine, normal protein function can sometimes be restored.

The development of a child begins during pregnancy, when prenatal environmental factors and genetic influences interact to ...

The study of gene interactions and biological processes is at the forefront of contemporary biological research, providing critical insights into the intricate networks that govern cellular function ...

The AHA recommended whole exome or whole genome sequencing as first-line diagnostic tools for mitochondrial diseases.

Alzheimer's disease (AD), a neurodegenerative disorder marked by amyloid plaque buildup and cognitive decline, remains a challenging condition to understand at the molecular level. While substantial ...

A new study has developed a powerful computational method that can detect how genes interact with each other to influence complex traits in humans at a scale previously impossible. The new method was ...

IDgenetix is a clinically validated pharmacogenomic (PGx) test that incorporates the results of drug-gene interactions with drug-drug interactions and lifestyle factors, such as smoking and use of ...

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.) Arun Durvasula, University of Southern California (THE CONVERSATION) Sitting in my ...