A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in ...

Using CRISPR technology, scientists uncovered genes that control C-A-G genetic stumbles in Huntington's disease ...

Symptoms of Huntington's disease appear late in life. Research reveals how DNA repeats grow toxic over time, explaining the ...

Huntington's disease, a fatal hereditary brain disorder, is linked to a genetic mutation that remains harmless for decades before expanding and producing toxic proteins that kill brain cells.

A scientific statement regarding CPET interpretation in patients with congenital HD across their lifespan has been published by the AHA.

A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over time but doesn't start causing harm until it hits a toxic threshold ...

At the moment, the only therapies for HD address the symptoms of the disease, and pridopidine is vying to become the first drug approved to slow down its clinical progression, offering a lifeline ...

The team found that although functions such as movement, thinking or behavior remained normal for a long time before the onset of symptoms in Huntington's disease, subtle changes to the brain were ...

This type of "somatic expansion" occurs in only the specific types of brain cells that later die in Huntington's disease. Only once a cell's DNA expansion reaches a threshold number of CAGs ...

Regeneron Pharmaceuticals has announced results from the phase 3 QUASAR trial and its extension study of the phase 3 PULSAR ...