The major histocompatibility complex (MHC) represents a critical gene family in vertebrates that shapes immune recognition and disease resistance through its extraordinary allelic diversity.

The adaptive immune system is an antigen-specific structure that discriminates non-self molecules through the recognition of peptide antigens using receptor interactions between T-cells and ...

Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor immunity. This review synthesizes emerging mechanistic evidence showing that ...

It is well known that the biggest genetic risk factor for the autoimmune disease systemic lupus erythematosus (SLE) is major histocompatibility complex class II (MHC-II). What remains unclear is the ...

Westlake Therapeutics (Hangzhou) Co. Ltd. and affiliated organizations have reported the design and preclinical characterization of novel erythrocytes conjugated to major histocompatibility complex ...

Modifying the organ instead of the recipient isn’t a new idea, but it is an important one, said Jeffrey Platt, a transplantation biologist at the University of Michigan Medical School who was not ...