In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...

Visualization of the genome (green) and a single gene (magenta) in a human cell nucleus, with genomic motions mapped by arrows and an example of a gene trajectory highlighted as a colored curve. A ...

The artificial cell nucleus (right) constructed using the purified DNA was morphologically very similar to the natural cell nucleus derived from an egg (left). A team led by Professor Kazuo Yamagata ...