Huntington's disease (HD) is a hereditary neurodegenerative disorder ... of the caudate nucleus on brain imaging. Today, DNA testing can reliably diagnose HD and differentiate the disease from other ...

Huntington’s disease was long thought to be caused by the slow buildup of a toxic protein, but new research has reveale | This week on "The Top Line," we hear from Steven McCarroll, Ph.D., whose ...

detectable through advanced imaging, blood and spinal fluid analysis, happen approximately 20 years before a clinical motor diagnosis in people with Huntington's disease, finds a study led by UCL ...

HD is a rare, adult-onset, autosomal dominant, progressive neurodegenerative disease. George Huntington (Figure 1) was the first person to provide a comprehensive description of adult-onset HD in ...

A study published in Nature Medicine reveals subtle neurodegenerative changes in people with Huntington’s disease gene expansion up to 20 years before symptoms appear. Using advanced imaging, blood ...

ElevateBio is seeking out partnerships for its lead gene therapy after the construct reduced the levels of a toxic protein in ...

LETI-101 has demonstrated therapeutically relevant reductions of mutant huntingtin (HTT) protein, exceeding 80%, while preserving essential ...

Brain Changes in Huntington's Disease Decades Before Diagnosis Will Guide Future Prevention Trials Jan. 17, 2025 — Subtle changes in the brain, detectable through advanced imaging, blood and ...