Huntington’s disease is one of the most common inherited neurodegenerative disorders that typically begins in adulthood and worsens over time. Patients begin to lose neurons in specific regions ...

Huntington’s disease was long thought to be caused by the slow buildup of a toxic protein, but new research has reveale | This week on "The Top Line," we hear from Steven McCarroll, Ph.D., whose ...

such as a selective loss of neurons within the central nervous system and a slow progression of neurological deficits. Therefore, the pathophysiology of Huntington's disease is likely to be ...

The stem cells were developed into neurons from the striatum, the brain region primarily impacted by Huntington's disease, making the model relevant to disease conditions. These neurons were then ...

Huntington's disease kills a population of cells called striatal projection neurons, which are located in the striatum, a structure deep in the brain responsible for movement, many cognitive ...

Huntington’s disease is a devastating neurodegenerative condition affecting ... of neurofilament light chain (NfL), a protein released into the spinal fluid when neurons are injured, and reduced ...

Striatal neurons, which express FOXP1 (yellow ... “This work has important implications beyond Huntington’s disease,” agreed Michael Guo of the University of Pennsylvania in Philadelphia (comment ...

ElevateBio is seeking out partnerships for its lead gene therapy after the construct reduced the levels of a toxic protein in ...

HDBuzz reported live updates on Bluesky from the 2025 HD Therapeutics Conference. Read on for coverage of Day 2. #CHDI2025 ...