For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor cell ...

Johns Hopkins Medicine scientists say they have developed a simplified version of biodegradable nanoparticles that can “educate” the immune system to find and destroy disease-causing cells throughout ...

Innate immune sensors—known as pattern recognition receptors (PRRs)—detect specific molecular components of bacterial or ...

Type 1 diabetes (T1D) is an autoimmune disease characterized by the immune-mediated destruction of pancreatic B cells. While autoreactive T cells are key ...

A schematic overview illustrating how the immune microenvironment is involved in diseases across various systems, including respiratory, cardiovascular, and digestive systems. Targeting cellular ...

Machine learning reveals unique COVID vaccine immune signatures in people living with HIV, with differences in antibodies, cytokines, and T cell responses.

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...

It is generally agreed that a number of types of nutritional deficiencies, including vitamin D-deficient rickets, can cause a temporary state of immune deficiency. As a result, children with rickets ...

Researchers identified dietary proteins that shape oral tolerance through intestinal regulatory T cells. Learn how food antigens may train immune tolerance.