Exactly 200 years after the discovery of the trace element selenium, researchers have shown for the first time why this chemical element is indispensable for mammalian life. As integral part of the ...

Researchers have developed a technique for selectively targeting and controlling the interneurons of the cerebellar molecular layer relying on a genetically engineered mouse model that exploits a ...

This is a preview. Log in through your library . Abstract Single interneurons influence thousands of postsynaptic principal cells, and the control of interneuronal excitability is an important ...

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a first-of-its-kind roadmap detailing how stem cells become sensory interneurons - ...

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have, for the first time, coaxed human stem cells to become sensory interneurons -- the cells ...

Cortical interneurons (cINs) modulate excitatory neuronal activity by providing local inhibition. During fetal development, several cIN subtypes derive from the medial ganglionic eminence (MGE), a ...

Northwestern Medicine investigators have uncovered new insights into the synaptic connections of subgroups of interneurons, findings that may improve the understanding of fear responses and could ...

The expression "once bitten, twice shy" is an illustration of how a bad experience can induce fear and caution. How to effectively reduce the memory of aversive events is a fundamental question in ...

Researchers from the MRC Centre for Developmental Neurobiology (MRC CDN) at King´s College London, led by Prof. Oscar Marín, have identified the mechanisms guiding interneurons to the striatum, a ...

One hypothesis for the death of motor neurons in amyotrophic lateral sclerosis (ALS) is that the neurons become hyperexcited, firing overtime and ultimately being poisoned by their own activity (Rao ...