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C1QL1 protein identified as key to myelin replacement - MSNAfter mice were fed a drug that destroys myelin, recovery of oligodendrocytes and myelination were delayed in mice lacking the C1QL1 protein. Causing mice to express more C1QL1, however, led to ...
Rather, the team found, the RNA latches on to a protein called SOX10, and together they turn on production of myelin basic protein, which zips myelin into a tight sleeve around nerve cells.
The current study analyzed the synthesis of myelin basic protein (MBP), a substance which is essential for the formation and stabilization of myelin membranes.
The working group has already identified protein molecules such as Sox10 that regulate the formation and preservation of myelin sheaths.
In rodents, the researchers found that the RNA transcript of RetroMyelin regulates the expression of myelin basic protein, one of the key components of myelin.
In rodents, the researchers found that the RNA transcript of RetroMyelin regulates the expression of myelin basic protein, one of the key components of myelin.
The working group has already identified protein molecules such as 'Sox10' that regulate the formation and preservation of myelin sheaths.
New research published in The FEBS Journal reveals the importance of a protein called C1QL1 for promoting the replacement of the specialized cells that produce myelin.
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