To cause tuberculosis, the bacterium Mycobacterium tuberculosis must obtain nutrients from host cells. This is facilitated at least in part by protein complexes known as transporters. The structure of ...

Besides their normal role, pump overexpression confers drug resistance. Knowing the structure is a step to disabling the pumps with inhibitors BIRMINGHAM, Ala. – Tuberculosis is the world’s leading ...

Tuberculosis is one of the top ten causes of death worldwide, infecting about one-quarter of the world's population. Although it is treatable, the rise of multidrug-resistant tuberculosis poses a ...

To support drug discovery, a new study has revealed fundamental features of the transcription cycle in the bacteria that causes tuberculosis.

In a lab in the heart of Boston, professor Bree Aldridge leads a team of researchers trying to understand a threat that is both microscopic in size and global in consequence. The subject of Aldridge’s ...

Tuberculosis is a severe infectious disease that usually affects your lungs. When it spreads to your bones, it's known as skeletal tuberculosis. Tuberculosis is an airborne disease caused by a very ...