After mice were fed a drug that destroys myelin, recovery of oligodendrocytes and myelination were delayed in mice lacking the C1QL1 protein. Causing mice to express more C1QL1, however, led to ...

Pup brains were examined at P7 for myelin basic protein (MBP) in the internal and external capsules using immunohistochemistry. Quantification of MBP mRNA was also undertaken.

In this image, an axon appears in green, while abnormal protein clumps (amyloid, red) lodge in tiny channels within the myelin sheath. Amyloid aggregates form filament-like strands across the ...

Other major myelin constituents include myelin basic protein (MBP), proteolipid protein (PLP), and myelin oligodendrocyte glycoprotein (MOG).

Rather, the team found, the RNA latches on to a protein called SOX10, and together they turn on production of myelin basic protein, which zips myelin into a tight sleeve around nerve cells.

In rodents, the researchers found that the RNA transcript of RetroMyelin regulates the expression of myelin basic protein, one of the key components of myelin.

The working group has already identified protein molecules such as Sox10 that regulate the formation and preservation of myelin sheaths.

Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients: a marker of activated/memory T cells.

DNA parasite now plays key role in making critical nerve cell protein An RNA has been adopted to help the production of myelin, a key nerve protein.

Kedia and colleagues found the Serpina3n oligodendrocytes had swelled with myelin basic protein (MBP), and their processes had fragmented, suggesting they were overwhelmed with myelin. Scanning ...

Typically, these cocultured oligodendroglia begin to form myelin within several weeks, says Tsai. The researchers noted this effect in the APOE3 coculture, “but in the APOE4 coculture, we saw ...