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Other major myelin constituents include myelin basic protein (MBP), proteolipid protein (PLP), and myelin oligodendrocyte glycoprotein (MOG).
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C1QL1 protein identified as key to myelin replacement - MSNAfter mice were fed a drug that destroys myelin, recovery of oligodendrocytes and myelination were delayed in mice lacking the C1QL1 protein. Causing mice to express more C1QL1, however, led to ...
VRK-1 phosphorylates acidic proteins, such as phosvitin and casein, and basic proteins such as histone 2b and myelin basic protein.
To better understand any pathological processes related to Alzheimer's disease that might affect the myelin sheath, Yale researchers analyzed proteins in human brain tissue, focusing on the sub ...
DNA parasite now plays key role in making critical nerve cell protein An RNA has been adopted to help the production of myelin, a key nerve protein.
The working group has already identified protein molecules such as Sox10 that regulate the formation and preservation of myelin sheaths.
Moreover, MAPK signalling-mediated phosphorylation controls the ability of the RNA-binding protein to stabilize the inherently unstable MAPK phosphatase mRNA, consequently leading to a negative ...
Rather, the team found, the RNA latches on to a protein called SOX10, and together they turn on production of myelin basic protein, which zips myelin into a tight sleeve around nerve cells.
Zasadzinski, Husted and Israelachvili also discovered that the myelin basic protein acts as a patch to fill in any holes in the myelin bilayers.
The Duncan NRI team found novel roles for the Dishevelled associated activator of morphogenesis 2 (Daam2) protein and CK2α kinase in regulating myelin repair and regeneration.
Using biochemical approaches, they found two amino acid residues (Ser704 and Thr705) of Daam2 protein undergo phosphorylation - a common post-translational regulatory mechanism that turns on or ...
Regenerating Myelin In The Brain Could Be Possible Thanks To New Discovery The newly discovered pathway could help scientists find treatments for diseases like multiple sclerosis.
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