Temperature is a key physiological factor that determines the speed of immune reactions. While this may seem obvious, it has remained largely unexplored at the single-cell level-until now.

With intensifying global warming and climate change, drought has become a major threat to global agriculture, impacting crop yields and food security. To survive such adverse events, plants have ...

"This process appears to be regulated by myosin-binding protein-C (cMyBP-C), which is a heart muscle protein," study author Kerry McDonald said. "Our study investigated its role in cardiac muscle ...

Myosin Therapeutics, Inc., a clinical-stage biotechnology company developing first-in-class therapies that modulate molecular ...

Using technologies like electron microscopy (EM) it is possible to capture molecular mechanisms in great detail, but not when these mechanisms are currently moving. The field of cryomicroscopy ...

In one of two trials that substantially expand clinical evidence with myosin inhibitors in the treatment of hypertrophic cardiomyopathy (HCM), a next-in-class agent beat beta-blockers in first-line ...

Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window The FDA approved ...

The novel cardiac myosin inhibitor aficamten improved peak oxygen uptake in symptomatic obstructive hypertrophic cardiomyopathy (HCM), the pivotal SEQUOIA-HCM trial showed. At 24 weeks, the mean ...

Each year, about 14,000 people in the United States are diagnosed with glioblastoma, one of the deadliest primary brain tumors. With standard treatments of surgery, radiation, and chemotherapy ...