The simplest one is to wager on the in-form golfers, a list led by Rory McIlroy and Scottie Scheffler. McIlroy may get the nod over Scheffler in some circles this week because he's playing on home soil at Royal Portrush in Northern Ireland.

SportsLine golf expert Eric Cohen locked in a $10 eight-leg PGA Tour parlay that would return nearly $1.1 million for the British Open 2025

Brooks Koepka enters play in the 2025 Open Championship at Royal Portrush Golf Club with +5500 odds to win. In his last event at this course he finished fourth in the 2019 The Open Championship. In his four tournaments during the past year, Koepka has a best finish of 12th and an average finish of 28th, with two made cuts.

It's the final round of the 2025 British Open golf tournament at Royal Portrush. Follow for live score updates and highlights, plus how to watch.

But nobody should ever mistake artificial intelligence for being sappy. USA TODAY Sports canvassed five major AI programs seeking their predictions for the 2025 Open Championship winner and top sleeper picks. The majority went with the pre-tournament favorite, Scottie Scheffler, who is seeking his first Claret Jug.

Robert MacIntyre, who placed sixth in the 2019 The Open Championship at Royal Portrush Golf Club, comes into the 2025 Open Championship with +3500 odds to win as he tries for another strong performance. In the past 12 months, MacIntyre has played in 23 tournaments. His best finish was second, and his average finish was 27th, with one top five.

Jason Sobel on the oldest tradition at the Open Championship, betting, and how it is more enjoyable than ever.

Scottie Scheffler and Rory McIlroy are favorites at the 2025 Open Championship. Here's where the rest of the 156-golfer field at Royal Portrush stands