With laboratory methods and diagnostics advancing apace, Francesca Lake considers whether PCR is likely to retain its crown as an essential lab method, or whether it could be replaced and consigned to ...

Detection and/or amplification of target DNA sequences by polymerase chain reaction (PCR) is a prevalent method in molecular biology. PCR has a broad range of applications, including use in research ...

The transmission of viruses through biological materials is of great concern to many researchers and managers of lab animal facilities. There is ample documentation 1 for the confounding effects of ...

When it comes to detecting rare cancer-causing mutations, both sensitivity and specificity matter. In the past few years, digital PCR (dPCR) has captured the attention of researchers and clinicians ...

A team of UK-based scientists has recently developed an allele-specific probe polymerase chain reaction method that can accurately detect different variants/lineages of severe acute respiratory ...

Please give an overview of microsatellite instability (MSI) status and its applications within oncology. Historically Microsatellite Instability (MSI) has been used to screen for Lynch Syndrome, a ...

Researchers at Imperial College London say they have developed a novel lab-on-a-chip infection test that could provide less expensive and faster portable diagnostics. The chip, known as TriSilix, is a ...

After a microbiology-filled academic and research career, Diana Patzelt became the Global Project Manager for Microbial Enumeration Products at Sartorius (Göttingen, Germany), earning her the title of ...

One of the best ways to figure out how far a virus like COVID-19 has spread in a community is to test for it. This step-by-step guide explains how coronavirus swab-the-nose-and-throat tests work, and ...