Systemic injection of adenovirus has an excellent tropism towards hepatocytes. This can be exploited to target adenoviral-based vectors to this organ, as has been extensively documented in mouse ...
After the cells were incubated with doxycycline (−) or (+) medium for 48 h, expression levels of p53-associated or -downstream proteins were compared. Stably transfected cells showed induced p53 ...
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