The host cell system is a critical determinant of recombinant protein quality and yield, with direct influence on protein folding and post-translational modification factors that shape the ...

Janelia researchers have uncovered a novel way that two of the structures inside cells—the endoplasmic reticulum (ER) and lysosomes—coordinate the production of proteins, highlighting how interactions ...

A study published in the Proceedings of the National Academy of Sciences has uncovered new clues to why some therapeutic proteins are so difficult to manufacture. The work—led by Nathan Lewis, PhD, ...

To address population growth and agricultural resource constraints, scientists developed an electrolytic gas-lift reactor for efficient hydrogen-oxidizing bacterial single-cell protein (HOB-SCP) ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During ...

The functioning of neurons, cells that transmit information in the nervous system, heavily relies on the production of ...

Escherichia coli remains at the forefront of recombinant protein production, owing to its rapid growth, well-characterised genetics and the ease with which it can be genetically manipulated. The ...

A previously unknown mechanism that makes it possible for aggressive so-called triple-negative breast cancer to fine-tune its production of proteins has been discovered by researchers at Umeå ...

Targeted protein degradation presents a promising strategy to address antimicrobial resistance, focusing on innovative ...

Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at ...