(A) The basic organization of a sarcomere subregion, showing the centralized location of myosin (A band). Actin and the z discs are shown in red. (B) A conceptual diagram representing the ...

They observed that one zone of the repeated sarcomere arrangement, the "A band," remained relatively constant in length during contraction (Figure 2A). The A band contains thick filaments of ...

Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...