The Panthers hit the road to take on the 49ers on Monday Night Football. The 49ers/Panthers game starts at 8:15 p.m. ET on ESPN. Yes! Peyton and Eli will be on ESPN2 for tonight’s 49ers/Panthers matchup.

Fans can listen to Monday Night Football live with SiriusXM on channel 88, NFL Radio, for the national broadcast. Team-specific calls are available on channel 225 (49ers broadcast) and 226 (Panthers broadcast).

The Panthers have one quarterback listed on the injury report: Bryce Young (FP/ankle): 197 Pass Comp; 314 Pass Att; 62.7 Pass Comp%; 1962 Pass Yds; 14 Pass TDs; 23 Rush Att; 83 Rush Yds; 1 Rush TD

Led by Bryce Young, the Panthers have exceeded expectations to this point in the season/ Following Sunday night’s Bics’ loss, Carolina is now tied for first in the NFC South. They also are a single game behind San Francisco for the final Wild Card spot in the playoffs.

San Francisco 49ers quarterback Brock Purdy's return should terrify the rest of the NFC, as he unlocks a different level for their offense.

On the heels of a very notable Week 12 and heading into a crucial Week 13, the NFL playoff picture is slowly coming into focus.