A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has ...

A research team has discovered that docosahexaenoic acid (DHA), a major omega-3 fatty acid found in fish oil, directly relaxes smooth muscle in the male reproductive tract by blocking specific calcium ...

A research group has uncovered important details about how platelet-activating factor (PAF)—a powerful molecule involved in inflammation and allergic reactions—triggers contractions in the smooth ...

A research team at Toho University has revealed that ferulic acid (FA), a polyphenol abundant in rice bran, suppresses intestinal smooth muscle contractions by inhibiting voltage-dependent calcium ...

Colonic motility disorders, especially problems associated with constipation and diarrhea, are common in adults and children, greatly impacting quality of life. A new study in The American Journal of ...

Ferulic acid suppresses ileal smooth muscle contraction by inhibiting calcium ion influx through voltage-dependent calcium channels. This action may help prevent or treat excessive intestinal motility ...

The contractile responses of esophageal smooth muscle (SM) induced by platelet-activating factor (PAF) involve the activation of L-type voltage-dependent calcium channels (L-type VDCCs), ...