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Lipid domains control myelin basic protein adsorption and membrane interactions between model myelin lipid bilayers. Proceedings of the National Academy of Sciences, 2014; 111 (8): E768 DOI: 10. ...
To better understand any pathological processes related to Alzheimer's disease that might affect the myelin sheath, Yale researchers analyzed proteins in human brain tissue, focusing on the sub ...
The working group has already identified protein molecules such as Sox10 that regulate the formation and preservation of myelin sheaths.
Proteins control all vital processes in every organism, for example growth and metabolism. A basic principle of protein research is that the structure of each protein determines its function.
The current study analyzed the synthesis of myelin basic protein (MBP), a substance which is essential for the formation and stabilization of myelin membranes.
Researchers who developed protein folding software, and used it to predict new, useful proteins win the Nobel.
Other major myelin constituents include myelin basic protein (MBP), proteolipid protein (PLP), and myelin oligodendrocyte glycoprotein (MOG).
Rather, the team found, the RNA latches on to a protein called SOX10, and together they turn on production of myelin basic protein, which zips myelin into a tight sleeve around nerve cells.
Expression of myelin basic protein (MBP)—the building block of myelin sheaths—was also lower in the hippocampi of older mice.
In this image, an axon appears in green, while abnormal protein clumps (amyloid, red) lodge in tiny channels within the myelin sheath. Amyloid aggregates form filament-like strands across the ...