The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

opening a pore to release its contents into the synapse. A fusion pore, the opening that occurs when a vesicle binds to a cell membrane, is present for just hundreds of microseconds, a thousand times ...

Similarly, tethering interactions are likely to be involved in concentrating synaptic vesicles at the synapse 41. In polarized epithelial cells, the mammalian Exocyst, the Sec6–Sec8 complex ...

The study introduces new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment. This ...

By electron microscopy, prominent accumulations of vesicles, the size of synaptic ... function along with neurexin and neuroligin in synapse formation, and how are the molecular interactions ...

There are two types of removal: Re-uptake – the neurotransmitter is reabsorbed back into the presynaptic neuron and restored inside a vesicle ready to be used again. For example, noradrenaline.