A new microscope method reveals details that were difficult to see before, helping researchers study proteins, cells, and ...

Conceptual illustration of the bidirectional quantitative scattering microscope, which detects both forward and backward scattered light from cells. This dual detection enables visualization of ...

Stretching protein samples in all directions pulls molecules farther apart, allowing them to be visualized using only light ...

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which garnered a Nobel Prize in 1953, brought into clear view structures inside ...

Scientists at Lawrence Berkeley National Laboratory made a big leap in their research into all things small. Within the past few months, scientists there began using what they say is the world’s most ...

In 1931, physicists Knoll and Ruska unveiled the first electron microscope, revolutionizing science by using magnetic lenses ...

Materials scientists can learn a lot about a sample material by shooting lasers at it. With nonlinear optical microscopy—a specialized imaging technique that looks for a change in the color of intense ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th-century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

In this review, we will look ahead and discuss potential future avenues of fluorescence imaging with light-sheets. We will describe how volumetric and temporal imaging barriers limit the application ...

Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this ...

Conceptual illustration of the bidirectional quantitative scattering microscope, which detects both forward and backward scattered light from cells. This dual detection enables visualization of ...