Stress granules are an integral part of the stress response that are formed from non-translating mRNAs aggregated with proteins. While much is known about stress granules, the factors that drive their ...

Asymmetric messenger RNA (mRNA) localization facilitates efficient translation in cells such as neurons and fibroblasts. However, the extent and importance of mRNA polarization in epithelial tissues ...

The nuclear export protein (XPO1) inhibition restored METTL3 localization and SG formation and increased mRNA expression. The authors posit that rescuing METTL3 localization could be explored as a ...

Recent progress in the development of high-content technologies for in-cell RNA visualization and imaging has revolutionized the exploration of mRNA biology and analysis of RNA-protein interactions.

Scientists at the University of California, Irvine, have discovered that nuclear speckles, a membraneless organelle within the nucleus, serve as central hubs for pre-mRNA 3′ end processing. This ...

A recent study has unveiled an exciting discovery about how our cells defend themselves during stressful situations. The research shows that a tiny modification in the genetic material, called ac4C, ...