Diagnostic nerve biopsy provides an instructive case history of the developmental arc of a laboratory test. Biopsy of peripheral nerves became a clinically applicable procedure around 40 years ago, ...

About half of a small group of patients with fibromyalgia -- a common syndrome that causes chronic pain and other symptoms -- was found to have damage to nerve fibers in their skin and other evidence ...

In this study we demonstrate an early loss of small nerve fibers detected by both CCM and skin biopsy in recently diagnosed T2D, with CNFD-MNF being most sensitive among six measures of CCM. However, ...

Background and aims: Normative values are lacking regarding intraepidermal nerve fiber density (IENFD) in thin sections of 5 µm. Thus, we aimed to assess IENFD in thin sections in a healthy adult ...

What meaning does decreased nerve conduction amplitude have in light of normal conduction velocity and normal muscle testing on EMG? The morphology of the peripheral nerve response is formed by the ...

Small diameter nerve fibers reach out to the surface of the skin, and their damage is often marked by development of burning pain in the feet. But routine nerve tests, like nerve conduction, and ...

Nerve damage is one of the most common and burdensome complications of diabetes. Millions of patients worldwide suffer from ...

Small fiber neuropathy occurs as a result of damage to the small fibers of the peripheral nervous system. Damage to the peripheral nervous system that affects the small fibers can cause burning pain ...

"This is a significant step towards personalized bioelectronic medicine," said Dr. Zanos. "This i2CS treatment gives us the ability to fine-tune nerve stimulation, activating fibers that produce ...

Results of a small study of people with tingling pain in their hands and feet have added to evidence that so-called prediabetes is more damaging to motor nerves than once believed, report scientists.