Diagnostic nerve biopsy provides an instructive case history of the developmental arc of a laboratory test. Biopsy of peripheral nerves became a clinically applicable procedure around 40 years ago, ...

Background and aims: Normative values are lacking regarding intraepidermal nerve fiber density (IENFD) in thin sections of 5 µm. Thus, we aimed to assess IENFD in thin sections in a healthy adult ...

In this study we demonstrate an early loss of small nerve fibers detected by both CCM and skin biopsy in recently diagnosed T2D, with CNFD-MNF being most sensitive among six measures of CCM. However, ...

About half of a small group of patients with fibromyalgia -- a common syndrome that causes chronic pain and other symptoms -- was found to have damage to nerve fibers in their skin and other evidence ...

Small fiber neuropathy occurs as a result of damage to the small fibers of the peripheral nervous system. Damage to the peripheral nervous system that affects the small fibers can cause burning pain ...

Nat Clin Pract Neurol. 2007;3(6):331-340. The finding of inflammatory lesions in PDN initially came as a surprise; however, it is now clear that complex relationships exist between obesity and type 2 ...

Nerve damage is one of the most common and burdensome complications of diabetes. Millions of patients worldwide suffer from ...

Prolonged, often disabling, small-fiber neuropathy in long COVID may be caused by a defective immune response, a small longitudinal study suggested. Peripheral neuropathy was identified in 59% of 17 ...

"This is a significant step towards personalized bioelectronic medicine," said Dr. Zanos. "This i2CS treatment gives us the ability to fine-tune nerve stimulation, activating fibers that produce ...

MANHASSET, N.Y.--(BUSINESS WIRE)--Researchers at the Feinstein Institutes for Medical Research have developed a groundbreaking new method for vagus nerve stimulation (VNS) that offers unprecedented ...