Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating hereditary disorder that strikes ...

ROCHESTER, N.Y. — Rochester Police are searching for a missing 10-year-old boy last seen on the city’s northwest side. Joseph ...

The prime minister of Pakistan has ordered an investigation over an ad by the country’s flag carrier that was criticized as ...

Vikings running back Aaron Jones, 49ers tight end George Kittle and Chargers defensive end Morgan Fox are the finalists for ...

A widely seen video of an 11-year-old girl handcuffed and crying on a snowy sidewalk has prompted criticism of an upstate New York sheriff’s office. Deputies with the Onondaga County Sheriff’s Office ...

U.S. defense contractor Anduril Industries is preparing to build a massive advanced manufacturing facility in central Ohio, ...

Senate hearings are scheduled this week for several of Trump’s picks for the Cabinet. While many are rapidly gaining support ...

ROCHESTER, N.Y. — A car was damaged in a crash overnight on St. Paul Street, a block away from Roberto Clemente School No. 8.

ROCHESTER, N.Y. — A line of Rochester Police cars shut down Salina Street off Chili Avenue for an investigation overnight.

The number of Americans applying for unemployment benefits rose last week, but layoffs remain historically low.

Pope Francis has fallen and hurt his right arm. It's the second time in a month that Francis has injured himself after an ...

Police say the death toll in a monthslong standoff between authorities and miners trapped while working illegally underground ...