Epoxide hydrolases (EHs) are enzymes that catalyse the conversion of epoxides to diols, making them indispensable in the synthesis of enantiopure compounds. Their inherent ability to perform ...

Epoxides belong to a class of organic compounds called “cyclic ethers” that are characterized by a three-atom ring. They are readily available compounds found in medicinal and agrochemical agents, as ...

Can making ephemeral anti-inflammatory fatty acids stick around a little longer protect people against Alzheimer’s disease? It just might, according to a study by Hui Zheng and colleagues at the ...

Epoxide ring-opening reactions may seem straightforward, but altering between acidic and basic conditions completely changes which carbon gets attacked. Basic conditions favor nucleophilic attack at ...

A reaction scheme showing a cyclohexyl epoxide undergoing a rearrangement and ring-contraction reaction to give a cyclopentane product. Researchers at the Southern University of Science and Technology ...

Assessment of cardiovascular (CV) toxicity by providers in advanced prostate cancer (PCa) patients (pts) on novel hormonal therapy (NHT). This is an ASCO Meeting Abstract from the 2025 ASCO ...

Neuropn Therapeutics LLC has divulged piperidine urea derivatives as bifunctional epoxide hydrolase 2 (EPHX2; sEH) inhibitors reported to be useful for the treatment of Parkinson's disease, pain, ...

Epoxide, a cyclic ether, can be used to obtain important alcohols, pharmaceuticals, agrochemicals, and functional polymers. This transformation is facilitated by the reductive ring opening of epoxide.