TRIM21, an enzyme involved in intracellular substrate degradation, can recognize viruses and bacteria that enter the cytosol when they are coated with antibodies. Just as it tags complex molecules for ...

The microbiome and a frontline innate antimicrobial sensor, Toll-like receptor 5 (TLR5), play an essential role in the ...

ADC Therapeutics SA blamed patients’ advanced age on the death imbalance in the phase III Lotis-5 confirmatory trial testing Zynlonta (loncastuximab tesirine-lpyl) in combination with rituximab to ...

Genome-wide association studies (GWAS) have identified multiple loci associated with complex diseases, but these are mostly ...

Shares of ADC Therapeutics SA (NYSE:ADCT) were trading at $1.54, down 49%, or $1.54, after the firm disclosed top-line data from the phase III Lotis-5 confirmatory trial testing Zynlonta ...

Oppenheimer analyst Jay Olson trumpeted “a new era” in pancreatic ductal adenocarcinoma (PDAC) after Revolution Medicines Inc ...

IMU Biosciences Ltd. has closed its series A at £40 million (US$53.9 million), adding £28.5 million to the initial close in ...

Shares of Fulcrum Therapeutics Inc. (NASDAQ:FULC) fell 54% after the company said it is discontinuing work on sickle cell ...

Eli Lilly and Co. has signed another billion-dollar deal, this time with Boston-based Ascidian Therapeutics Inc., a company that is barely four years old and one that is focused on treating human ...

Less than two months after winning FDA approval for a second indication for Filspari (sparsentan), Travere Therapeutics Inc.

At the 2026 American Society of Clinical Oncology annual meeting, multiple companies presented data for their drugs targeting ...

Minneapolis-based Celcuity Inc. was like the Rolling Stones at the 2026 American Society of Clinical Oncology annual meeting.