See related article at A crisis of communicable diseases is unfolding in North America, just as Canada’s health systems’ responses are being hampered by the dismantling of public health and research ...

The incidence of chlamydia and gonorrhea, 2 common sexually transmitted infections, is increasing. Annual asymptomatic screening for chlamydia and gonorrhea should be performed in all sexually active ...

Iron deficiency and iron deficiency anemia are common during pregnancy and are associated with adverse outcomes Prenatal iron deficiency occurs in more than 30% of pregnancies in Canada. 1 It has been ...

In research published in this issue of CMAJ, Mah and colleagues summarize clinicians’ experiences of providing care for patients whose presenting illness is not acute and for whom admission to ...

KEY POINTS Genitourinary syndrome of menopause (GSM) is common and can be treated with over-the-counter vaginal lubricants or supplementation with vaginal estrogen. Vaginal energy devices (such as CO2 ...

KEY POINTS Severe anemia and myelosuppression are rare but serious complications of azathioprine that are more likely to occur at high doses or when potentiated by interactions with other drugs.

BACKGROUND: Prognostication tools that report personalized mortality risk and survival could improve discussions about end-of-life and advance care planning. We sought to develop and validate a ...

A pregnant, primiparous 32-year-old woman at 28 weeks’ gestation presented for a routine prenatal visit. Blood work showed thrombocytopenia with platelet count of 60 (reference range 130–380) × 109/L.

Figure 1: Nickel allergic contact dermatitis: (A) Periumbilical skin of a 41-year-old man with 2 erythematous plaques with overlying pruritic and eczematous papules. (B) A marked improvement was ...

KEY POINTS Multifactorial early-pregnancy screening for preeclampsia can identify most patients at risk, particularly of early-onset, severe disease. Prophylaxis with acetylsalicylic acid (ASA) can ...

Since the last Canadian acne guideline was published in 2000, 17 evidence for multiple additional treatments has been published. Thus, there was an unmet need for an updated, systematically developed, ...