About 5% of Canadians are affected by sinonasal inflammation.[1][1] There is broad expert consensus supporting the effectiveness of intranasal corticosteroids for treating allergic and nonallergic ...

Iron deficiency and iron deficiency anemia are common during pregnancy and are associated with adverse outcomes Prenatal iron deficiency occurs in more than 30% of pregnancies in Canada. 1 It has been ...

See related article at A crisis of communicable diseases is unfolding in North America, just as Canada’s health systems’ responses are being hampered by the dismantling of public health and research ...

BACKGROUND: Prognostication tools that report personalized mortality risk and survival could improve discussions about end-of-life and advance care planning. We sought to develop and validate a ...

KEY POINTS Multifactorial early-pregnancy screening for preeclampsia can identify most patients at risk, particularly of early-onset, severe disease. Prophylaxis with acetylsalicylic acid (ASA) can ...

In research published in this issue of CMAJ, Mah and colleagues summarize clinicians’ experiences of providing care for patients whose presenting illness is not acute and for whom admission to ...

A pregnant, primiparous 32-year-old woman at 28 weeks’ gestation presented for a routine prenatal visit. Blood work showed thrombocytopenia with platelet count of 60 (reference range 130–380) × 109/L.

KEY POINTS Severe anemia and myelosuppression are rare but serious complications of azathioprine that are more likely to occur at high doses or when potentiated by interactions with other drugs.

KEY POINTS Genitourinary syndrome of menopause (GSM) is common and can be treated with over-the-counter vaginal lubricants or supplementation with vaginal estrogen. Vaginal energy devices (such as CO2 ...

Figure 1: Nickel allergic contact dermatitis: (A) Periumbilical skin of a 41-year-old man with 2 erythematous plaques with overlying pruritic and eczematous papules. (B) A marked improvement was ...

The results presented by Fran Paradiso-Hardy and colleagues1 are an excellent example of formal Bayesian causality assessment2 of a series of reported cases of suspected adverse drug reactions to ...