During his 36-year career at Cancer Center, Michael Emerman, PhD, made fundamental discoveries about HIV, the retrovirus that causes AIDS. He co-founded the field of paleovirology and considers ...

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

Molecules from the 20-million-year-old teeth of a rhino relative are among the oldest ever sequenced, opening tantalizing ...

In the interview, Lloyd M. Smith discusses proteoforms, an area of research worthy of the next Human Genome Project.

Unlike the brain and spinal cord, peripheral nerve cells, whose long extensions reach the skin and internal organs, are ...

Suddenly feeling old? Evidence now suggests that rather than a long, steady decline, we dramatically age around three ...

Scientists in recent years have made progress in finding ancient DNA in fossils, gaining insight into organisms that lived ...

Leiden researchers have discovered an enzyme that helps bacteria feed on everyday plastics. This common enzyme could play a ...

These results confirm the importance of positive selection in proteins related to defense mechanisms already observed in a wide array of organisms. Key words: pathogenesis-related proteins, PRs, ...

Here, we review recent advances in studies of protein translocation employing single-molecule techniques with the aim of resolving molecular mechanisms, thereby providing a new and detailed view of ...

The PDB has created systems for the processing, exchange, query, and distribution of data that will enable many aspects of high throughput structural genomics.

When the flavor diffuses into the interior of the protein molecule, it destroys the hydrophobic interaction between the protein chain segments and destabilizes the protein structure, thus changing the ...