research suggests that certain dopaminergic pathways may also be important in relieving depression-like symptoms. Research in humans has demonstrated that for some individuals with treatment-resistant ...

This is because dopamine plays a crucial role in emotional regulation through the “mesolimbic dopaminergic pathway,” which governs reward-related behavior and stress responses. When you engage ...

Northwestern Medicine investigators have uncovered new insights into how metabolic dysfunction contributes to Parkinson's ...

A subset of Parkinson’s disease is caused by CHCHD2, a gene which encodes a protein contained in the mitochondria of cells.

in particular those associated with the nigrostriatal dopaminergic pathway. There is now robust experimental evidence for a neuroprotective effect of nicotine upon dopaminergic neurons.

Precision drugs and gene therapy treatments to activate pro-survival pathways in selected neuronal populations We investigate molecular mechanisms promoting functional maintenance of dopaminergic ...