eLife10d
Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway
Notch1 is expressed uniformly throughout the mouse endocardium during the initial stages of heart valve formation, yet it remains unclear how Notch signaling is activated specifically in the AVC ...
Heart29d
Advancing clinical management of left ventricular thrombosis: prevention, detection and treatment modalities in the modern era
Heightened interest in left ventricular thrombus (LVT) stems from the consistent association of subsequent stroke and ...
eLife21d
Transplantation of exogenous mitochondria mitigates myocardial dysfunction after cardiac arrest
Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...
Nature1d
Differentiation articles from across Nature Portfolio
Cell differentiation is the process by which specialised cells such as muscle, skin or nerve cells, are formed from less specialised cells such as stem cells and their progenitors. Differentiation ...
Europe PMC16d
Assessment of myocardial work in sarcomere gene mutation carriers, healthy controls and overt nonobstructive hypertrophic cardiomyopathy.
A single centre study with a case-control design. Patients with overt nonobstructive HCM and a causal sarcomere gene variant (n = 44), carriers (n = 51) and age and sex matched (to the carriers) ...