A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease ...

Brain Changes in Huntington's Disease Decades Before Diagnosis Will Guide Future Prevention Trials Jan. 17, 2025 — Subtle changes in the brain, detectable through advanced imaging, blood and ...

Huntington’s disease symptoms are linked to expanding DNA repeats (CAG) that become toxic in brain cells over time The "ticking DNA clock" accelerates after 80 repeats, killing neurons within ...

The team found that although functions such as movement, thinking or behavior remained normal for a long time before the onset of symptoms in Huntington's disease, subtle changes to the brain were ...

The team found that although functions such as movement, thinking or behaviour remained normal for a long time before the onset of symptoms in Huntington's disease, subtle changes to the brain ...

according to the Huntington’s Disease Association. If a parent has the condition, their children have a 50/50 chance of inheriting the faulty gene developing the condition. Symptoms include ...

Huntington's disease, a fatal hereditary brain disorder, is linked to a genetic mutation that remains harmless for decades before expanding and producing toxic proteins that kill brain cells.

Researchers have made a major breakthrough in our understanding of Huntington's disease. This genetic disorder has long been known to be caused by mutations in the huntingtin gene, which leads to the ...