A team of researchers has discovered that a protein called cypin plays a powerful role in helping brain cells connect and ...

Scientists at ETH Zurich have broken new ground by generating over 400 types of nerve cells from stem cells in the lab, far ...

Differential ultrastructural localization of myelin basic protein, myelin/oligodendroglial glycoprotein, and 2’,3’-cyclic nucleotide 3’-phosphodiesterase in the CNS of adult rats.

Myelin-specific T lymphocytes are considered essential in the pathogenesis of multiple sclerosis. The myelin basic protein peptide (a.a. 83–99) represents one candidate antigen; therefore, it ...

Iron oxide nanoparticles (IONPs) have become one of the most promising nanomaterials for biomedical applications because of their biocompatibility and physicochemical properties. This study ...

In this image, an axon appears in green, while abnormal protein clumps (amyloid, red) lodge in tiny channels within the myelin sheath. Amyloid aggregates form filament-like strands across the ...

Protein kinase C-related kinases (PRKs) are members of the protein kinase C superfamily of serine-threonine kinases and can be activated by binding to members of the Rho family of GTPases via a ...

Demonstrates that neuregulin 1 type III isoforms are the crucial isoforms required for survival of SCPs, for axon fasciculation and for motor and sensory neuron survival in peripheral nerves.

The structural integrity, and thus function, of paranodes rely on septate-like junctions, which are unique structures comprising neurofascin isoform 155 (NF155) on myelin loops, and heterodimers of ...