Subsequent sequencing analysis of the miRNAs within these vesicles revealed that M-Ang2-EVs enhance microglial phagocytosis of myelin, promote axonal remyelination and extension, and regulate tight ...
This study presents a valuable finding on the function of the gene Cst7 in sex-divergent pathological changes in microglia in a mouse model of amyloid-driven Alzheimer's disease. The evidence ...
We performed (i) quantitative spatial profiling of the mRNA transcript encoding myelin basic protein (MBP), (ii) quantification of MBP protein and (iii) the first quantitative structural assessment of ...
Impact of stress on diseases including gastrointestinal failure is well-known, but molecular mechanism is not understood. Here we show underlying molecular mechanism using EAE mice. Under stress ...
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